Gradient Biotech

Host-pathogen integration

Group episode outcomes by a pathogen or host feature carried in versioned cross-area results, preserving the originating area, run, and version.

Research question

Do outcomes differ by pathogen lineage, resistance, or a host feature produced in another area — without recomputing that area's science here?

Who this is for

  • Translational infection researchers relating pathogen features to outcomes
  • Teams combining Microbiology lineage/AMR results with clinical episodes
  • Analysts who need provenance retained across linked evidence

Data requirements

DataRequiredPurpose
Episodes with outcomesYesThe outcome to group and compare
Linked results referencing another areaYesFeature (e.g. lineage) grouping by episode
Feature key in the linked result summaryRecommendedWhich summary field to group by

Workflow

Link versioned Microbiology/CompBio/Immunology results by episode
  → Run integration with a feature key (e.g. lineage)
  → Review outcomes grouped by feature, with provenance
  → AI interpretation

Step 1 — Link results

Record cross-area results against the correct episode and specimen. Each link keeps the area, run id, method, and version — the integration contract is shared subject/episode/specimen identity, not a copied pipeline.

Step 2 — Integrate

The Integration analysis groups episode outcomes by a feature (such as lineage) from the linked result summaries and reports each group's event rate together with its linked provenance.

Expected outputs

  • Outcome groups by pathogen/host feature with event rates
  • Linked provenance table (area, run, version, result type)
  • Counts of episodes and linked results integrated

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