Gradient Biotech

Overview

Cardiology workflows connect physiological signal ingestion, validated metrics, cohort comparison, and AI interpretation in a single study workspace. Each use case below maps a common research question to platform capabilities, data requirements, and a suggested analysis path.

Use case index

Use caseResearch questionKey capabilities
Holter HRV analysisWhat are the HRV and signal quality characteristics of this recording?ECG preprocessing, HRV metrics, waveform explorer, AI interpretation
ECG morphology phenotypingWhat are the PR, QRS, QT/QTc, and ST characteristics of this recording?ECG delineation, morphology metrics, landmark overlay, AI interpretation
Longitudinal wearable HRVHow does HRV change over a long recording, and how variable is it?Sliding-window HRV, trends, windowed cohort comparison
Stress and activityWhat do electrodermal and motion signals add, and is HRV motion-contaminated?EDA tonic/phasic + SCRs, accelerometer activity, cross-modal motion quality
Pulse-wave and transit-time analysisWhat do PPG pulse shape and ECG-to-PPG timing reveal about vascular state?PPG pulse morphology, pulse arrival/transit time (PAT/PTT)
Wearable RR cohortHow do HRV metrics differ across a wearable or Holter-export cohort?RR CSV ingestion, batch HRV, cohort comparison
Multimodal autonomic profilingHow do HRV, blood pressure, and respiration interact for this subject?Cross-modal pipelines — baroreflex, RSA, mechanistic interpret
Cohort outcomesDo physiological metrics differ by treatment group or associate with outcomes?Group comparison, statistical tests, research risk stratification

Who these use cases serve

AudienceTypical goals
Cardiovascular researchersECG, HRV, telemetry, BP, PPG analysis with reproducible pipelines
Hospital research groupsCohort analysis, signal quality filtering, treatment-response comparison
Wearable and digital health teamsLarge-scale RR/PPG processing, artifact detection, feature extraction
Pharma and clinical trial teamsPhysiological signal endpoints, digital biomarkers, longitudinal analysis

Common data requirements

Most use cases start with a cardiology study containing:

  • Datasets — ECG waveforms, RR interval CSVs, PPG, blood pressure, or respiration recordings
  • Subjects (for cohort use cases) — participant metadata with treatment group, diagnosis, and optional outcomes
  • Completed pipeline runs — preprocess and HRV runs linked to subjects for cohort comparison

Choosing a starting point

If your primary data is…Start with…
Single ECG or Holter recordingHolter HRV analysis
ECG intervals and waveform shape (QT, QRS, ST)ECG morphology phenotyping
Long recordings where HRV changes over timeLongitudinal wearable HRV
EDA, accelerometer, and motion-aware ECG qualityStress and activity
PPG pulse shape / cuffless-BP timing (paired ECG+PPG)Pulse-wave and transit-time analysis
RR interval CSVs from wearablesWearable RR cohort
ECG + BP + respiration for one subjectMultimodal autonomic profiling
Multi-subject study with group labelsCohort outcomes

What these use cases are not

These workflows support exploratory cardiovascular research. They are not clinical decision support or diagnostic tools. Arrhythmia outputs are burden metrics for research. Risk stratification is research-only. All AI interpretation outputs include disclaimers and cite computed metrics only.

Next steps